metal fume fever

Fumes are formed by evaporation at high temperature and condensation in air into fine particles. acute respiratory distress syndrome (ARDS), rapid onset of symptoms (5-10 hours) following exposure to the fumes, fever, rigors, arthralgia, myalgia, headache, malaise, generally, the condition is self-limiting with no long term sequelae. Inhaling many freshly formed metallic oxides, such as those of zinc, cadmium, copper, etc may lead to acute influenza-like illness termed metal fume fever. Polymer fume fever is a related, yet distinct, condition. An occupational disorder caused by the inhalation of fumes or metallic oxides; characterized by symptoms similar to influenzas. Pulmonary infiltrates and hypoxemia are not consistent with pure metal fume fever. Chest imaging usually shows clear lung parenchyma and CT may show mild atelectasis or pleural effusions. Zinc chloride exposure may occur from smoke bombs; although it can cause severe lung injury, it does not cause metal fume fever. Terms of Use A history of welding, especially on galvanized metal, and typical symptoms and signs are sufficient to make the diagnosis. Blood or urine zinc determinations do not have a role in clinical diagnosis of the syndrome. Enhanced elimination. 3. {"url":"/signup-modal-props.json?lang=us\u0026email="}. With the exception of exposure to cadmium fume serious complications are rare.   •  Privacy Policy Rare asthmatic or allergic responses to zinc oxide fume have been reported. Metal fume fever has a very long list of historic synonyms, related to its historic association with zinc working, including Monday fever, brazier disease, brass founder’s ague, brass chills, copper colic, zinc fever, zinc fume fever, zinc chills, copper fever, foundry fever, spelter’s shakes, smelter’s chills, the shakes, the smothers, galvanised shakes, galvanizer’s poisoning, welder's ague, acute brass poisoning, galvo and metal shakes 1-3. Nevertheless, up to 2,500 cases are still diagnosed in the USA per annum, and in Victoria, Australia, 85 cases were identified in a retrospective study looking at the preceding 5.5 years: Exposing metal to very high temperatures, such as occurs in welding, and related processes, results in the emanation of "metal fumes", which are defined as solid submicron-sized particles formed by the condensation of aerosolized metal compounds 1. Copyright © McGraw HillAll rights reserved.Your IP address is The toxic dose is variable. Provide symptomatic care (eg, acetaminophen or another antipyretic) as needed; symptoms are self-limited. Treatment tends to be supportive and in the vast majority recovery is rapid. Metal fume fever usually occurs in workplace settings involving welding, melting, or flame-cutting of galvanized metal (zinc-coated steel), or in brass foundry operations. The mechanism is uncertain but may be cytokine-mediated. Diagnosis. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. The air level considered immediately dangerous to life or health (IDLH) is 500 mg/m3. Unable to process the form. These responses are not part of the metal fume fever syndrome. This site uses cookies to provide, maintain and improve your experience. LXII (4): 296.   •  Accessibility. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. Otherwise it is hidden from view. Specific levels. • Systemic poisoning. Metal fume fever is a (typically) self-limiting disease due to exposure to fumes emanating from working metal, e.g. There is no specific antidote. The white blood cell count may be elevated (12,000–16,000/mm3). The underlying pathogenesis is still being researched but is likely secondary to both immune and non-immune mediated mechanisms. Although the fumes can contain a wide range of metals including zinc, copper, manganese, chromium, iron, titanium, cadmium and nickel. [27.] https://accessmedicine.mhmedical.com/content.aspx?bookid=391§ionid=42069914. If your institution subscribes to this resource, and you don't have a MyAccess Profile, please contact your library's reference desk for information on how to gain access to this resource from off-campus. any chemical element marked by luster, malleability, ductility, and conductivity of electricity and heat, and which will ionize positively in solution. brass) are heated to high temperatures. The main cause of this exposure is usually breathing the fumes from welding, cutting, or brazing on galvanized metal. The chest radiograph is usually normal. metal fume fever: [ met´'l ] any chemical element marked by luster, malleability, ductility, and conductivity of electricity and heat, and which will ionize positively in solution. Mechanism of toxicity. Typically, all symptoms resolve on their own within 24–36 hours. : Cytokines in, [28.] welding. Symptoms typically begin 4–8 hours after exposure with fever, malaise, myalgia, and headache. If present, this suggests possible heavy metal pneumonitis resulting from cadmium or other toxic inhalations (eg, phosgene and nitrogen oxides) associated with metal working, foundry operations, or welding. Therefore symptoms tend to maximize in severity on the first return to work after a weekend or any time away from the workplace. Metal fume fever. https://accessmedicine.mhmedical.com/content.aspx?bookid=391§ionid=42069914. https://medical-dictionary.thefreedictionary.com/metal+fume+fever. No deaths have been recorded. The relative proportions of the various metals are conditional upon the form of welding employed, the metals being worked, etc. 172.81.118.151 If hypoxemia or wheezing is present, consider other toxic inhalations (See Gases, Irritant). Metal fume fever results from inhalation of zinc oxide (neither ingestion nor parenteral administration induces this syndrome). There are no specific tests to diagnose or exclude metal fume fever.   •  Notice BRAZIER'S DISEASE, BRASS-FOUNDER'S AGUE, OR ACUTE BRASS-POISONING. (1914) Journal of the American Medical Association. welding. There is no role for these procedures. (2015) Clinical toxicology (Philadelphia, Pa.). Decontamination is not necessary; by the time symptoms develop, the exposure has usually been over for several hours. alkali metal one of a group of monovalent elements including lithium, sodium, potassium, rubidium, and cesium. Much less commonly, bilateral patchy ground-glass opacities, or even consolidations, may be seen, with an appearance mimicking acute respiratory distress syndrome (ARDS). The commonest cause of metal fume fever is welding galvanized steel. Metal fume fever is an acute febrile illness associated with the inhalation of respirable particles (fume) of zinc oxide. : An experimental human model of, Dictionary, Encyclopedia and Thesaurus - The Free Dictionary, the webmaster's page for free fun content, HEALTH HAZARDS RESULTING FROM EXPOSURE TO ZINC AND ITS INORGANIC COMPOUNDS IN INDUSTRY/ZAGROZENIA ZDROWOTNE WYNIKAJACE Z NARAZENIA NA CYNK I JEGO ZWIAZKI NIEORGANICZNE W PRZEMYSLE, Metal Finishes & Finishing Processes & Procedures, Metal Finishing Association of Southern California, Metal Finishing Facility Risk Screening Tool, Metal Forming Machinery Makers' Association. It was first described in the mid-1800s among brass foundry workers and in the early 1900s in welders of galvanized steel.1 Over the years, it has been known by a variety of names, including Monday fever, brass founders’ The condition is most likely to occur in poorly ventilated areas in the metal-working industry. First published case is from 1831 1. Greenberg MI, Vearrier D. Metal fume fever and polymer fume fever. 53 (4): 195-203. Metal fume fever is an acute febrile illness associated with the inhalation of respirable particles (fume) of zinc oxide.

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